منابع مشابه
Imaging basal ganglia function.
In this review, the value of functional imaging for providing insight into the role of the basal ganglia in motor control is reviewed. Brain activation findings in normal subjects and Parkinson's disease patients are examined and evidence supporting the existence for functionally independent distributed basal ganglia-frontal loops is presented. It is argued that the basal ganglia probably act t...
متن کاملStriatal inhomogeneities and basal ganglia function.
It has always been something of a mystery as to why different diseases of the basal ganglia may produce completely opposite effects on movement. Thus, defective dopaminergic inhibitory input into the striatum in Parkinson’s disease causes an akinetic-rigid syndrome, while destruction of the striatum in Huntington’s disease usually causes chorea. This theoretic paradox may be resolved by more de...
متن کاملStriatal Plasticity and Basal Ganglia Circuit Function
The dorsal striatum, which consists of the caudate and putamen, is the gateway to the basal ganglia. It receives convergent excitatory afferents from cortex and thalamus and forms the origin of the direct and indirect pathways, which are distinct basal ganglia circuits involved in motor control. It is also a major site of activity-dependent synaptic plasticity. Striatal plasticity alters the tr...
متن کاملHandbook of Basal Ganglia Structure and Function
It has been more than three decades now since B.S. Bunney, G.K. Aghajanian and their colleagues at Yale published the first electrophysiological studies of midbrain dopamine (DA) neurons in vivo ( Bunney et al., 1973a,b ). These extracellular single unit recordings revealed that DA neurons in the substantia nigra (SN) pars compacta (SNc) and ventral tegmental area (VTA) of chloral hydrate-anest...
متن کاملFunctional magnetic resonance imaging evidence for disrupted basal ganglia function in schizophrenia.
OBJECTIVE This study was an examination of basal ganglia dysfunction in schizophrenia using functional magnetic resonance imaging (fMRI). METHOD The authors used a motor sequencing task to investigate activation of the caudate, anterior putamen plus globus pallidus, and posterior putamen plus globus pallidus in eight subjects with schizophrenia and 12 group-matched comparison subjects. Differ...
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ژورنال
عنوان ژورنال: Journal of Anatomy
سال: 2000
ISSN: 0021-8782,1469-7580
DOI: 10.1046/j.1469-7580.2000.19640543.x